Central Research Institute (CRI) is pioneer in the field of vaccines not only in India but in the world. Founded on 3rd of May 1905, the institute was originally established with a mandate of research work in the field of medical and public health, manufacture of vaccines and antisera, human resource development and to act as a national referral centre for public health problems. The contribution of the Institute towards vaccine production during the period of the Second World War for the immunization of troops to keep them fighting, finds no parallel.
The institute has set various milestones during its journey over last 113 years. During this period the institute has been continuously contributing to the National Health Programme through manufacture of life saving immunobiologicals, surveillance activities, teaching and training in the field of microbiology.
Recent developments in regulatory requirements and introduction of Schedule M concept in vaccine manufacturing emphasized the need of cGMP compliant infrastructure and processes. Considering the need of cGMP compliance to keep pace with advances in regulatory requirements and technological developments, CRI has been able to create cGMP compliant facility for production of DPT group of vaccines. Creation of cGMP compliant DPT production facility has made CRI as the first Central Government Institute to have cGMP compliant infrastructure for vaccine production.